Dorsal Root Ganglion (DRG) Stimulation | Minimally Invasive Pain Relief Skip to Content

Dorsal Root Ganglion (DRG) Stimulation

Procedures

Dorsal root stimulator diagram

What Is Dorsal Root Ganglion Stimulation?

Dorsal Root Ganglion (DRG) Stimulation is a cutting-edge, minimally invasive neurostimulation therapy used to manage chronic, nerve-related pain. A small implantable device delivers precise electrical pulses to the dorsal root ganglia—clusters of sensory nerves just outside the spinal cord.

By modulating nerve activity, DRG stimulation interrupts pain signals before they reach the brain, reducing or eliminating the perception of pain. Unlike traditional spinal cord stimulation (SCS), DRG therapy targets very specific pain regions, making it especially effective for patients with focal neuropathic pain.

Conditions Treated with DRG Stimulation

  • Complex Regional Pain Syndrome (CRPS): One of the most well-supported uses.
  • Chronic Neuropathic Pain: Especially in the foot, ankle, knee, groin, or pelvic areas.
  • Post-Surgical or Traumatic Nerve Injury Pain: For example, after hernia repair, knee replacement, or ankle surgery.
  • Pain Unresponsive to Other Treatments: Including medications, injections, or standard spinal cord stimulation.
  • Chronic burning, stabbing, or electrical pain in a specific region (foot, knee, groin, pelvis).
  • CRPS-related hypersensitivity, where even light touch is painful.
  • Nerve-related pain that disrupts sleep, mobility, or quality of life.
  • Patients with severe, localized nerve pain interfering with daily life.
  • Individuals who did not find relief with spinal cord stimulation or conservative therapies.
  • Candidates willing to undergo a trial period with temporary electrodes before committing to permanent implantation.
  • Exclusions may include:
    • Active infection.
    • Uncontrolled psychiatric conditions.
    • Poor surgical tolerance.
    • Unrealistic expectations about outcomes.
Doctor patient consultation before drg stimulator procedure

What to Expect: Before, During, and After

Before

  • Comprehensive evaluation of pain history and prior treatments.
  • Imaging studies (MRI, CT, or X-ray) to assess spine anatomy.
  • Psychological assessment to ensure readiness for implant therapy.
  • Detailed discussion of expectations, risks, and benefits.
  • Step 1: Trial Phase: Temporary electrodes are placed under fluoroscopy (X-ray guidance) and connected to an external device.
    • Patients test stimulation for 5–10 days to confirm meaningful pain relief.
  • Step 2: Permanent Implantation: If the trial is successful, a small pulse generator is implanted under the skin, and permanent leads are positioned near the targeted DRG nerves.
  • Device is programmed and fine-tuned in the clinic.
  • Patients can adjust their stimulation levels using a handheld controller.
  • Follow-up visits ensure proper healing, programming optimization, and rehab integration.
Married middle age couple riding bicycles

Expected Outcomes and Results

Results

  • Many patients experience 50–80% pain reduction after implantation.
  • Relief is often long-lasting and stable over years.
  • Greater ability to participate in physical therapy and daily activities.
  • Studies report improved patient satisfaction, mood, and quality of life compared to other neurostimulation therapies.

Like all procedures, DRG stimulation carries some risks:

  • Surgical risks: infection, bleeding, or scar tissue formation.
  • Lead migration or device malfunction.
  • Temporary soreness at the implant site.
  • Rare cases of overstimulation or inadequate relief.
  • Device replacement may be needed after several years (battery life depends on usage).
  • Targeted pain relief for specific regions (more precise than traditional spinal cord stimulation).
  • Fewer side effects such as numbness, tingling, or unwanted stimulation.
  • Sustained pain control with adjustable programming.
  • Improved mobility, sleep, and mental well-being.
  • Reduction in opioid reliance, supporting safer, long-term pain management.
Provider performing a clinical pain assessment

Clinical Research

Extensive research—including randomized controlled trials—shows DRG stimulation provides superior results for CRPS and focal neuropathic pain compared to traditional spinal cord stimulation. Clinical studies demonstrate:

  • Higher success rates in pain reduction.
  • Improved functional outcomes (mobility, return to work, activity participation).
  • Greater patient satisfaction and sustained relief at 12–36 months follow-up.

Integrative Care at Holistiq Spine & Orthopaedic

Holistiq utilizes a multidisciplinary, non-surgical approach for chronic MSK conditions. We combine ESIs with:

For patients who require surgery, Holistiq coordinates with top surgeons and supports optimal pre- and post-op recovery using our integrative system.

Epidural steroid injections are one tool in a suite of evidence-based options to relieve MSK pain, restore function, and help you return to a better quality of life.

FAQs About Epidural Steroid Injections

How is DRG stimulation different from spinal cord stimulation?

DRG stimulation is more targeted, ideal for focal pain areas, while SCS often covers broader regions.

Most patients do not feel uncomfortable tingling. Relief is achieved without constant awareness of stimulation.

Yes, but the system can be removed or replaced if needed. The trial phase ensures suitability before implantation.

Pain relief can be immediate during the trial phase, and maintained after permanent placement.

Some devices are MRI-compatible. Always confirm with your provider and device manufacturer.

Why Choose Our Clinic?

We specialize in advanced neuromodulation therapies like DRG stimulation, combining expertise with individualized care. With careful screening, precise implantation, and personalized rehabilitation, we help patients achieve meaningful, long-term pain relief and reclaim quality of life.

Where Does It Hurt? We Can Help.

Holistiq understands that chronic pain can manifest in various ways. Our holistic approach addresses a wide range of conditions throughout your body, helping you find lasting relief. Explore the map below to understand what we treat.

Procedures